Applications are invited for a Research Scientist to join the Laboratory of Dr Gemma Langridge in the Microbes and Food Safety programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.
Background:
The Langridge group at QIB has a broad interest in bacterial diversity and metabolism, and the role that genetic variation plays in niche adaptation. By linking observed and engineered DNA mutations to their impact upon metabolic function, we gain insights into the biology of niche adapted bacteria including Salmonella and E. coli. We use a range of experimental techniques, including whole genome and metagenomic sequencing, metabolic phenotyping and transcriptomics, and use bioinformatic workflows and bespoke scripts to analyse our data.
The role:
We are seeking a microbiologist with bioinformatics skills to investigate the genetic basis of virulence in the bovine pathogen Salmonella enterica serovar Dublin. This is a collaborative project with the University of Edinburgh (UoE), where in vitro and in vivo phenotyping will take place.
The applicant will perform long-read sequencing of S. Dublin isolates at the project outset and undertake genomic variation analysis to investigate virulence in bovine and human hosts. The applicant will also sequence isolates from in vitro and in vivo phenotyping at UoE and work collaboratively with a research scientist from UoE to link genotype to phenotype.
The ideal candidate:
Candidates should hold a PhD in Microbiology or Bioinformatics or a related discipline and have a strong background in sequence analysis. They should have a good understanding of long and short read sequencing and an awareness of Salmonella zoonosis. Excellent organisational and communication skills are essential.
Additional information:
Salary on appointment will be within the range £36,720 to £39,750 per annum depending on qualifications and experience. This is a full-time post for a contract of 36 months.
For further information and details of how to apply, please visit our website
https://jobs.quadram.ac.uk or contact the Human Resources team on 01603 450814 or
[email protected] quoting reference 1004756. This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options.
We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.
As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
About the Quadram Institute:
The Quadram Institute is a new interdisciplinary research institute dedicated to understanding how food and microbes interact to promote health and prevent disease. Its mission is to deliver healthier lives through innovation in gut health, microbiology and food. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a state-of-the-art building on the Norwich Research Park. This is one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (
https://quadram.ac.uk/).
The closing date for applications will be 13 October 2024
The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.
