Applications are invited for a temporary post of a Post-doctoral Research Fellow Level 1 within UCD School of Biology and Environmental Science.
Competition Number - 018060
Promising new drugs for immunotherapy are so-called ‘innate immune checkpoint inhibitors’ that disrupt inhibitory ‘don’t eat me’ signals on macrophages, leading to enhanced cancer cell phagocytosis. The cancer cell-macrophage interaction is mediated by two proteins, namely CD47 and SIRP-alpha. Evidence suggests that disruption of this interaction can significantly enhance macrophage ability to engulf and destroy cancer cells and is therefore an exciting therapeutic avenue to follow. This project, in collaboration with the immunobiology laboratory of Professor Ulla Knaus, will involve the development of a microscopy-based high-content drug screen to identify candidate molecules that disrupt the cellular localisation of SIRP-alpha in primary macrophages.
This is a research focused role, where you will conduct a specified programme of research supported by research training and development under the supervision and direction of a Principal Investigator.
Salary Range: €44,847 - €47,412 per annum
Appointment on the above range will be dependent on qualifications and experience
Closing date: 12:00 noon (local Irish time) on the 20th of January 2025.
Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 12:00 noon (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.
UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned.
The PD1 position is intended for early stage researchers, either just after completion of a PhD or for someone entering a new area for the first time. If you have already completed your PD1 stage in UCD or will soon complete a PD1, or you are an external applicant whose total Postdoctoral experience, inclusive of the duration of the advertised post, would exceed 4 years, you should not apply and should refer to PD2 posts instead.
Prior to application, further information (including application procedure) should be obtained from the Work at UCD website:
https://www.ucd.ie/workatucd/jobs/
